NAIMS Workshop 2023
Ultra-High Field MRI in Multiple Sclerosis
February 21-22, 2023
Marriott Marquis San Diego Marina
San Diego, California
The North American Imaging in Multiple Sclerosis Cooperative (NAIMS) Workshop will be taking place Tuesday, February 21, and Wednesday, February 22 at the Marriott Marquis San Diego Marina in San Diego, California. The workshop will be held ahead of the ACTRIMS Forum 2023, being held February 23-25, 2023 at the Marriot San Diego Marina in San Diego.
The purpose of this workshop is to provide an overview of the state-of-the-art and future perspectives of ultra-high-field (UHF) MRI in multiple sclerosis (MS). This workshop will particularly focus on the contributions of 7-tesla (7T) imaging to our understanding of MS pathology and lesion development. Safety considerations and current technical challenges will also be discussed with the goal to facilitate the integration of 7T imaging in the clinical workflow. The workshop is targeted toward neurologists and radiologists interested in UHF MRI for clinical research/clinical practice, as well as MRI physicists and image processing scientists interested in developing novel techniques applicable to 7T imaging.
NAIMS Workshop Session Recordings
NAIMS Workshop (2023) recordings are available in the ACTRIMS Online Library (https://actrims.mclms.net/en/). These are currently only accessible to registered workshop attendees. General access to the recordings will be opened on April 15, 2023.
To access, please make sure you are signed into your ACTRIMS account, which you used to register for the NAIMS Workshop. You can use the “LOGIN” button on the top right or your screen and log in using your ACTRIMS credentials.
Organizing Committee
Corree Laule, University of British Columbia
Sridar Narayanan, McGill University
Pascal Sati, Cedars-Sinai Medical Center
Our Partners
Susan Gauthier, Weill Cornell University
Dan Harrison, University of Maryland
Eric Klawiter, Massachussetts General Hospital
Program Schedule
All times are listed in Pacific Time (PT). This schedule is subject to change.
+ Tuesday, February 21, 2023
| 7:30 - 8:30 am | Breakfast |
| 8:30 - 8:45 am | Welcome
Dan Harrison, University of Maryland, Baltimore VA Medical Center |
| 8:45 - 9:45 am | Ultra-High Field MRI-Histology Correlations
Chair: Pascal Sati, Cedars-Sinai Medical Center | |
| 8:45 - 9:15 am | Human Post-Mortem Ultra-High Field Imaging-Histology Correlations Francesca Bagnato, Vanderbilt University |
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| 9:15 - 9:45 am | Pre-Clinical Ultra-High Field Imaging-Histology Correlations Maxime Donadieu, National Institutes of Health, National Institute of Neurological Disorders and Strokes |
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| 9:45 - 10:15 am | Break |
| 10:15 am - 12:15 pm | Pathogenesis of MS Informed by 7T Imaging
Chair: Caterino Mainero, Harvard Medical School | |
| 10:15 - 10:45 am | Central Vein Sign Alessandro Cagol, University of Basel |
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| 10:45 - 11:15 am | Paramagnetic Rim Lesions Alberto Calvi, Hospital Clinic Barcelona |
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| 11:15 -11:45 am | Cortical Lesions Erin Beck, Mount Sinai |
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| 11:45 am -12:15 pm | Detection of Damage in Normal Appearing Tissue Cristina Granziera, University of Basel |
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| 12:15 - 1:00 pm | Lunch |
| 1:00 - 4:30 pm | 7T Opportunities & Technical Obstacles
Chair: Sridar Narayanan, Montreal Neurological Institute and Hospital, McGill University | |
| 1:00 - 1:30 pm | Metabolic Imaging (CEST, MRS) Peter Barker, Johns Hopkins University |
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| 1:30 - 2:00 pm | Magnetic Property Mapping (T2*, T1, MTR, Frequency, QSM, etc) David Rudko, Montreal Neurological Institute and Hospital, McGill University |
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| 2:00 - 2:30 pm | Multi-Nuclear Lazar Fleysher, Mount Sinai |
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| 2:30 - 3:00 pm | Break | |
| 3:00 - 3:30 pm | Myelin Imaging Jeff Duyn, National Institutes of Health, National Institute of Neurological Disorders and Strokes |
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| 3:30 - 4:00 pm | Spinal Cord Seth Smith, Vanderbilt University |
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| 4:00 - 4:30 pm | Diffusion Susie Huang, Massachusetts General Hospital, Harvard Medical School |
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| 4:30 - 4:45 pm | Break |
| 4:45 - 5:15 pm | Data Blitz
Chairs: Susan Gauthier, Cornell University & Corree Laule, University of British Columbia Cervical Spinal Cord Susceptibility Weighted MRI at 7T: Application to Multiple Sclerosis Atlee Witt, Vanderbilt University Changes in Gyrification in Multiple Sclerosis are Related to Cortical Lesion Load and Worsening Disability Jonadab Dos Santos Silva, Mount Sinai A Pilot Trial of Ocrelizumab for Modulation of Meningeal Enhancement in Multiple Sclerosis Shishir Dahal, University of Maryland |
| 5:15 - 6:15 pm | Reception |
+ Wednesday, February 22, 2023
| 7:30 - 8:30 am | Breakfast |
| 8:30 - 9:30 am | Technical Challenges: Safety, Artifacts, and Reproductibility
Chair: Sridar Narayanan, Montreal Neurological Institute and Hospital, McGill University | |
| 8:30 - 9:00 am | 7T MRI Safety, Artifacts, and Mitigation Strategies Mike Hoff, University of California, San Francisco |
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| 9:00 - 9:30 am | Multi-Center 7T Studies in MS Dan Harrison, University of Maryland, Baltimore VA Medical Center |
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| 9:30 - 10:00 am | Data Blitz
Chairs: Francesa Bagnato, Vanderbilt University & Rob Bakshi, Harvard Medical School Analysis of Meningeal Contrast Enhancement Volume on 7T MRI in Multiple Sclerosis Yohance Allette, University of Maryland, Baltimore VA Medical Center In Vivo MRI to Detect Potential Remyelination in a Nonhuman Primate Model of Multiple Sclerosis Maxime Donadieu, National Institutes of Health, National Institute of Neurological Disorders and Strokes 7T MRI Leptomeningeal Enhancement Longitudinal Dynamics and Association with Cognitive Function in Multiple Sclerosis: A 1-year Study Jon Zurawski, Brigham and Women’s Hospital, Harvard Medical School |
| 10:00 - 10:30 am | Break |
| 10:30 - 11:30 am | Integration of 7T Imaging in Clinical Workflow
Chair: Cristina Granziera, University of Basel | |
| 10:30 - 11:00 am | The North American Experience Jon Zurawski, Brigham and Women’s Hospital, Harvard Medical School |
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| 11:00 - 11:30 am | The European Experience Siegried Trattnig, Medical University of Vienna |
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| 11:30 am - 12:00 pm | Data Blitz
Chairs: Eric Klawiter, Massachusetts General Hospital & Alberto Calvi, Hospital Clinic Barcelona Performance Evaluation of Ensemble Algorithms Coupled with 7T MRI and Clinical Features for Predicting Multiple Sclerosis Progression Seongjin Choi, University of Maryland Using Phase Patterns to Differentiate Lesion Severity in Multiple Sclerosis Bryan Hernandez, The University of Texas at El Paso Diffusion MRI Biomarkers for Inflammation in Spinal Cord Sarah Morris, University of British Columbia |
| 11:30 - 1:15 pm | Lunch |
| 1:15 - 2:45 pm | Elements of a 7T MS Protocol: Technical Discussion
Chairs: Pascal Sati, Cedars-Sinai Medical Center & Sridar Naryanan, Montreal Neurological Institute and Hospital, McGill University |
| 2:45 - 3:15 pm | Break |
| 3:15 - 4:45 pm | Clinical Translation Discussion
Chairs: Dan Harrison, University of Maryland, Baltimore VA Medical Center & Eric Klawiter, Massachusetts General Hospital, Harvard Medical School |
| 4:45 - 5:00 pm | Conclusion & Final Remarks
Susan Gauthier, Cornell University & Corree Laule, University of British Columbia |
