NAIMS Workshop 2024

Imaging Barriers of the CNS

February 28, 2024
Hilton West Palm Beach
West Palm Beach, Florida

The North American Imaging in Multiple Sclerosis Cooperative (NAIMS) Workshop will be taking place Wednesday, February 28 from 8:00 am - 7:00 pm at the Hilton West Palm Beach in West Palm Beach, Florida. The workshop will be held ahead of the ACTRIMS Forum 2024, being held February 29-March 2 at the Palm Beach County Convention Center and Hilton West Palm Beach.

The purpose of this workshop is to provide a review of the structure, function, and physiology of CNS blood barriers, how these are affected in multiple sclerosis, and opportunities to use neuroimaging to better understand disease progression and therapeutic intervention in MS. The workshop is targeted towards neurologists and radiologists interested in MRI for clinical research/clinical practice, as well as MRI physicists and image processing scientists interested in developing novel techniques applicable to neuroimaging in MS.

Registration for the NAIMS Workshop 2024 closed on Wednesday, February 21, 2024.

Registration Fees
Delegate: professional employed by academic institution, hospital, government agency, or non-profit organization. $100
Young Investigator: student/trainee OR professional who has obtained an advanced degree (M.D. or Ph.D.) within seven years (2017 or later) of the time of the Forum. Proof is required. $50
Industry Representative: Professional who holds a non-research position and is employed by a pharmaceutical company or commercial entity. $150

Accommodations

There is limited availability at the Hilton West Palm Beach in West Palm Beach, Florida for attendees of the NAIMS workshop. Click below to book your hotel rooms or visit the ACTRIMS Forum 2024 Travel page to see additional availability at other area hotels.

Organizing Committee

  • Caterina Mainero, Harvard Medical School/Massachusetts General Hospital

  • Simone Sacco, University of California—San Francisco

  • Yunyan Zhang, University of Calgary

7:15 - 8:15 am Breakfast
8:00 - 8:10 am Welcome
William Rooney, Oregon Health & Science University

8:10 - 10:30 am CNS Barriers in Health & Disease
Moderators: Matthew Brier, Washington University in St. Louis and Christopher Hemond, UMass Memorial Medical Center
8:10 - 8:50 am Endothelial Barriers: Structure and Immune (Dys)Function
Britta Engelhardt, University of Bern, Switzerland
8:50 - 9:30 am Epithelial Barriers: Structure and Function in the Choroid Plexus
Richard Keep, University of Michigan
9:30 - 10:10 am Illuminating the Structure and Function of Meningeal Barriers
Dorian McGavern, National Institutes of Health
10:10 - 10:30 am Discussion

10:30 - 10:45 am Break

10:45 am - 12:00 pm Imaging Barrier Anatomy and Pathology in MS
Moderators: Richard Dortch, Barrow Neurological Institute and Simone Sacco, University of California—San Francisco
10:45 - 11:05 am White Matter: Dynamic Contrast MRI: Concepts and Applications in MS
William Rooney, Oregon Health & Science University
11:05 - 11:25 am Gray matter: Imaging Cortical Lesions
Caterina Mainero, Harvard Medical School/Massachusetts General Hospital
11:25 - 11:45 am Meninges: Characterizing MS LME Using MRI
Dan Harrison, University of Maryland
11:45 - 12:00 pm Discussion

12:00 - 1:00 pm Lunch

1:00 - 2:45 pm Imaging Markers: Emerging Opportunities
Moderators: Caterina Mainero, Harvard Medical School/Massachusetts General Hospital and William Rooney, Oregon Health & Science University
1:00 - 1:20 pm Imaging Neuroinflammation of Choroid Plexus MS
Neils Bergsland, University at Buffalo
1:20 - 1:40 pm Retina: Blood Retinal Barrier and Correlates with Brain Pathology in MS
Elizabeth Silbermann, Oregon Health & Science University
1:40 - 2:00 pm BBB Permeability Beyond Gadolinium; Water Permeability
Ian Tagge, Biogen
2:00 - 2:20 pm Perivascular Space: Enlargement in MS
Serhat Okar, National Institutes of Health
2:20 - 2:45 pm Discussion

2:45 - 3:00 pm Break

3:00 - 4:45 pm Breaking Barriers to Clinical [Trial] Translation
Moderators: Christopher Hemond, UMass Memorial Medical Center and Yunyan Zhang, University of Calgary
3:00 - 3:20 pm Disease Modifying Therapies and CNS Barrier Function
Stig Cramer, Glostrup Hospital/Region Hovedstaden
3:20 - 3:40 pm Conventional Imaging to Detect BBB Breakdown Without Contrast
Ponnada Narayana, University of Texas Health Science Center at Houston
3:40 - 4:00 pm Using PET to Image Treatment Response in MS
Matthew Brier, Washington University in St. Louis
4:00 - 4:20 pm Image Harmonization Across Institutions/Time Post-Acquisition
Roland Henry, University of California—San Francisco
4:20 - 4:45 pm Discussion

4:45 - 5:15 pm Lightning Presentations

5:15 - 5:30 pm Workshop Wrap-Up

5:30 - 7:00 pm NAIMS Workshop Reception & Poster Session
  • Bill Rooney, Chair, Oregon Health & Science University

  • Matthew Brier, Washington University in St. Louis

  • Richard Dortch, Barrow Neurological Institute

  • Christopher Hemond, UMass Memorial Medical Center

Our Partners

Program Schedule

The NAIMS Workshop will take place Wednesday, February 28, 2024. All times are listed in Eastern Standard Time (EST). This schedule is subject to change.